Hives (urticaria) affect millions of people worldwide, with up to 20% of the population experiencing this intensely itchy condition at some point during their lifetime. These raised, red welts can appear suddenly and cause significant discomfort and disruption to daily activities. Dr. Zitelli provides comprehensive urticaria treatment throughout Cincinnati, offering both immediate relief for acute episodes and long-term management strategies for chronic cases that persist beyond six weeks.
Not only provides excellent care but truly cares.
Understanding Acute and Chronic Urticaria Types
Urticaria presents in distinct patterns requiring different diagnostic and treatment approaches based on duration, triggers, and underlying mechanisms.
Acute Urticaria
Episodes lasting less than six weeks, often triggered by infections, medications, or foods, affecting 15-20% of people during their lifetime
Chronic Spontaneous Urticaria
Persistent hives lasting longer than six weeks without identifiable triggers, affecting approximately 0.7% of the population with significant quality of life impact
Chronic Inducible Urticaria
Hives triggered by specific physical stimuli including cold, heat, pressure, vibration, or exercise, requiring specialized testing for accurate diagnosis
Urticaria with Angioedema
Combined presentation of hives with deeper swelling affecting face, lips, eyelids, and potentially airways, requiring immediate medical evaluation
Dr. Zitelli’s Comprehensive Urticaria Assessment
Effective hives management requires thorough evaluation to identify potential triggers and determine appropriate treatment strategies. Dr. Zitelli’s systematic approach addresses both immediate symptom relief and long-term disease control.
“Understanding the specific type of urticaria is crucial for effective treatment. While acute hives often resolve quickly, chronic urticaria requires a comprehensive approach to identify triggers and provide sustained relief,” explains Dr. Zitelli.
Clinical Evaluation and Trigger Identification
Comprehensive urticaria assessment includes detailed history taking, physical examination, and targeted testing when indicated. Dr. Zitelli evaluates potential triggers including medications, foods, infections, and physical factors to develop personalized treatment plans.
Specialized Testing and Monitoring
For chronic cases, specialized testing may include dermatographism assessment, cold stimulation tests, and laboratory evaluation to rule out underlying autoimmune conditions or identify specific trigger factors.


Evidence-Based Treatment Approaches
Modern urticaria management offers multiple therapeutic options tailored to disease severity, duration, and individual patient factors.
Antihistamine Therapy
First-line treatment with non-sedating antihistamines at standard or increased doses, providing effective symptom control for most patients with acute episodes
Advanced Antihistamine Protocols
Higher-dose antihistamine regimens or combination therapy for patients with inadequate response to standard dosing, following established safety guidelines
Systemic Corticosteroids
Short-term prednisone courses for severe acute episodes or chronic cases during flares, carefully managed to minimize long-term side effects
Biologic Therapies
Omalizumab and other targeted treatments for antihistamine-resistant chronic urticaria, offering significant improvement in approximately 65% of refractory cases
Specialized Chronic Urticaria Management
Patients with chronic urticaria require ongoing care and monitoring to achieve optimal disease control and prevent complications.
Long-term Treatment Planning
Chronic urticaria management focuses on achieving complete symptom control while minimizing medication side effects. Dr. Zitelli develops individualized treatment plans that may include step-up therapy protocols and regular monitoring for treatment response.
Emergency Action Planning
Patients with severe urticaria or associated angioedema require emergency action plans including recognition of warning signs and appropriate use of emergency medications when airway involvement occurs.
Lifestyle Modifications and Trigger Avoidance
Comprehensive urticaria care extends beyond medication to include lifestyle modifications and trigger identification strategies that can significantly impact disease activity.
Patients learn to identify and avoid personal triggers while implementing stress management techniques and appropriate skin care routines. For physical urticarias, specific avoidance strategies and protective measures help prevent symptom development.
Frequently Asked Questions About Hives
Hives can be triggered by infections, medications, foods, stress, or physical factors, though in many cases of chronic urticaria, no specific trigger is identified.
Acute hives usually resolve within hours to days, while chronic urticaria can persist for months to years, though most cases improve significantly over time.
Modern non-sedating antihistamines are generally safe for long-term use, even at higher doses, when used under proper medical supervision.
Seek immediate medical attention if hives are accompanied by difficulty breathing, swallowing problems, or rapid swelling of face, lips, or throat.
While chronic urticaria often improves or resolves over time, treatment focuses on achieving symptom control and preventing complications rather than cure.

Board-Certified Dermatologist Serving Cincinnati, Ohio
Dr. Kristine Zitelli is a board-certified dermatologist serving the Cincinnati area, known for her expertise in treating a wide range of skin conditions. She completed her medical degree at Wright State University and dermatology residency at the University of Cincinnati, with additional advanced training at the UCSF Psoriasis and Skin Treatment Center. Her clinical focus includes thorough skin examinations, psoriasis, eczema, complex medical dermatology, surgical dermatology and cosmetic treatments using the latest technologies.
Dr. Zitelli has been named a “Top Doctor” in Cincinnati every year since 2016 as well as Cincinnati’s Top Dermatologist in 2020. She remains dedicated to educating the community about skin health and sun safety. Combining academic excellence, clinical research, and a compassionate approach, Dr. Zitelli delivers personalized, evidence-based care to every patient.
Achieve Lasting Hives Relief in Cincinnati
Don’t let urticaria control your daily life and comfort. Dr. Zitelli’s comprehensive approach to hives treatment combines immediate symptom relief with long-term management strategies, helping patients in Cincinnati and Montgomery achieve lasting control over their urticaria. Schedule your allergy skin consultation today to begin your path toward effective hives management.