Hyperhidrosis, or excessive sweating, affects approximately 4.8% of the US population–nearly 15.3 million people–making it more common than autism, psoriasis, or peanut allergies. This condition involves sweating far beyond what’s needed for normal body temperature regulation, often causing significant emotional distress and functional impairment. Dr. Zitelli provides comprehensive hyperhidrosis management throughout Cincinnati, offering both first-line treatments and advanced therapeutic options to help patients regain confidence and comfort in their daily lives.
Not only provides excellent care but truly cares.
Understanding Primary and Secondary Hyperhidrosis
Hyperhidrosis presents in different forms requiring specific diagnostic approaches and treatment strategies based on underlying causes and affected body areas.
Primary Focal Hyperhidrosis
Excessive sweating in specific body areas without underlying medical conditions, typically beginning in childhood or adolescence with bilateral symmetrical presentation
Secondary Hyperhidrosis
Generalized sweating caused by underlying medical conditions, medications, or metabolic disorders requiring treatment of the root cause
Palmar Hyperhidrosis
Excessive sweating of the hands affecting approximately 25% of hyperhidrosis patients, often causing significant occupational and social challenges
Axillary Hyperhidrosis
Underarm sweating affecting up to 68% of hyperhidrosis patients, frequently accompanied by odor concerns and clothing staining issues
Dr. Zitelli’s Comprehensive Hyperhidrosis Assessment
Effective hyperhidrosis treatment begins with thorough evaluation to determine the type, severity, and impact on daily functioning. Dr. Zitelli’s systematic approach ensures appropriate treatment selection for each patient’s specific needs and circumstances.
“Understanding the pattern and severity of excessive sweating helps us develop the most effective treatment plan. Many patients don’t realize how many successful treatment options are available for this challenging condition,” explains Dr. Zitelli.
Clinical Evaluation and Severity Assessment
Hyperhidrosis diagnosis relies primarily on clinical assessment and patient history. Dr. Zitelli evaluates sweating patterns, triggers, family history, and functional impact to determine the most appropriate treatment approach and rule out secondary causes.
Treatment Planning and Patient Education
Comprehensive hyperhidrosis care includes patient education about available treatment options, realistic expectations, and proper application techniques for topical therapies. Treatment plans are individualized based on severity, location, and patient preferences.


Evidence-Based Treatment Options
Modern hyperhidrosis management offers multiple therapeutic approaches from conservative topical treatments to more advanced interventions for severe cases.
Prescription Antiperspirants
Aluminum chloride formulations applied to dry skin at bedtime, providing effective first-line treatment for mild to moderate cases with proper application techniques
Oral Medications
Anticholinergic agents like glycopyrrolate that reduce sweating systemically, useful for patients with multiple affected areas or those who cannot use topical treatments
Botulinum Toxin Injections
FDA-approved neurotoxin injections that temporarily block nerve signals to sweat glands, providing 6-12 months of significant sweating reduction
Iontophoresis Therapy
Medical device treatment using electrical current to temporarily disable sweat glands, particularly effective for palmar and plantar hyperhidrosis with regular use
Advanced Management Strategies
Patients with severe or treatment-resistant hyperhidrosis may benefit from combination therapies and specialized treatment approaches.
Combination Treatment Protocols
Successful hyperhidrosis management often involves combining multiple approaches such as prescription antiperspirants with oral medications or periodic botulinum toxin treatments to achieve optimal symptom control while minimizing side effects.
Lifestyle Modifications and Supportive Care
Comprehensive hyperhidrosis management includes guidance on clothing choices, hygiene practices, stress management techniques, and strategies to minimize triggers that can exacerbate excessive sweating throughout daily activities.
Quality of Life Considerations
Hyperhidrosis significantly impacts patients’ psychological, social, and occupational functioning, making comprehensive care essential for addressing both physical symptoms and emotional wellbeing.
Studies show that 70% of hyperhidrosis patients experience severe sweating, yet only 51% discuss their condition with healthcare providers. Many patients avoid social situations, experience anxiety about physical contact, and face occupational limitations due to their condition.
Treatment Response and Monitoring
Successful hyperhidrosis management requires ongoing monitoring and treatment adjustments to maintain optimal symptom control and address changing patient needs over time.
Regular follow-up appointments allow for treatment effectiveness assessment, side effect monitoring, and therapy modifications as needed. Many patients require long-term management with periodic treatment adjustments to maintain quality of life improvements.
Frequently Asked Questions
Primary hyperhidrosis typically begins in childhood or adolescence due to overactive sympathetic nervous system responses, while secondary hyperhidrosis results from underlying medical conditions or medications.
Prescription-strength aluminum chloride antiperspirants can be highly effective when applied correctly to completely dry skin at bedtime, with success rates varying by body location and severity.
While injections cause temporary discomfort, most patients tolerate the procedure well, and the significant reduction in sweating typically outweighs the brief treatment discomfort.
Treatment duration varies by method: prescription antiperspirants require nightly use, oral medications work daily, botulinum toxin lasts 6-12 months, and iontophoresis requires regular sessions.
While no permanent cure exists, effective long-term management can provide significant symptom relief and dramatic quality of life improvements for most patients with appropriate treatment.

Board-Certified Dermatologist Serving Cincinnati, Ohio
Dr. Kristine Zitelli is a board-certified dermatologist serving the Cincinnati area, known for her expertise in treating a wide range of skin conditions. She completed her medical degree at Wright State University and dermatology residency at the University of Cincinnati, with additional advanced training at the UCSF Psoriasis and Skin Treatment Center. Her clinical focus includes thorough skin examinations, psoriasis, eczema, complex medical dermatology, surgical dermatology and cosmetic treatments using the latest technologies.
Dr. Zitelli has been named a “Top Doctor” in Cincinnati every year since 2016 as well as Cincinnati’s Top Dermatologist in 2020. She remains dedicated to educating the community about skin health and sun safety. Combining academic excellence, clinical research, and a compassionate approach, Dr. Zitelli delivers personalized, evidence-based care to every patient.
Control Your Excessive Sweating in Cincinnati
Don’t let hyperhidrosis limit your confidence and daily activities. Dr. Zitelli’s comprehensive approach to excessive sweating treatment combines proven therapies with personalized care, helping patients in Cincinnati and Montgomery achieve significant symptom relief and improved quality of life. Schedule your hyperhidrosis consultation today to explore effective treatment options tailored to your specific needs.