Lichen planus is a chronic inflammatory autoimmune condition affecting approximately 0.22-4% of the adult population, with women being affected twice as often as men. This T-cell mediated disorder causes characteristic purple, polygonal, pruritic papules and plaques that can affect the skin, oral mucosa, genitals, and nails. Dr. Zitelli provides comprehensive lichen planus management throughout Cincinnati, offering specialized autoimmune skin care approaches that address both acute flares and long-term disease control for this complex inflammatory condition.
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Understanding Lichen Planus Variants
Lichen planus presents in several distinct forms requiring specialized autoimmune skin care approaches based on location, severity, and associated symptoms.
Classic Cutaneous Lichen Planus
Most common form presenting as purple, flat-topped polygonal papules with characteristic Wickham striae, typically affecting wrists, ankles, and lower back
Oral Lichen Planus
Chronic mucosal variant affecting 50-70% of lichen planus patients, presenting as white lacy patterns or painful erosions inside the mouth requiring specialized care
Erosive Lichen Planus
Severe inflammatory variant causing painful ulcerations and erosions on mucous membranes, particularly challenging form requiring aggressive autoimmune management
Lichen Planopilaris
Scarring alopecia variant affecting the scalp with follicular destruction, potentially leading to permanent hair loss without appropriate early intervention
Dr. Zitelli’s Comprehensive Autoimmune Assessment
Effective lichen planus management requires understanding the autoimmune nature of this condition and developing personalized treatment strategies that address both inflammation and immune system dysfunction.
“Lichen planus represents a complex autoimmune process where the body’s T-cells attack healthy skin and mucous membrane cells. Our approach focuses on controlling inflammation while supporting overall immune system balance,” explains Dr. Zitelli.
Clinical Evaluation and Autoimmune Screening
Comprehensive lichen planus evaluation includes assessment of characteristic lesions, distribution patterns, and potential triggers while screening for associated autoimmune conditions and hepatitis C virus exposure, which shows strong association with lichen planus.
Specialized Autoimmune Skin Care Planning
Dr. Zitelli develops individualized autoimmune skin care protocols addressing inflammation control, barrier function restoration, and immune system modulation while monitoring for disease progression and treatment response.


Evidence-Based Autoimmune Skin Care Approaches
Modern lichen planus management combines topical anti-inflammatory therapies with systemic treatments when necessary to control this autoimmune inflammatory process.
High-Potency Topical Corticosteroids
First-line therapy for cutaneous and mucosal lichen planus, providing rapid inflammation control through immune suppression and anti-inflammatory effects
Topical Calcineurin Inhibitors
Steroid-sparing immunosuppressive agents like tacrolimus, particularly effective for oral and genital lichen planus with fewer long-term side effects
Systemic Immunosuppressants
Oral corticosteroids, methotrexate, or azathioprine for severe or widespread disease requiring systemic autoimmune control and inflammation management
Specialized Autoimmune Therapies
Advanced treatments including hydroxychloroquine, mycophenolate mofetil, or biologics for refractory cases requiring aggressive immune modulation
Advanced Autoimmune Management Strategies
Severe or treatment-resistant lichen planus may require specialized autoimmune approaches combining multiple therapeutic modalities for optimal disease control.
Erosive Disease Management
Erosive lichen planus requires intensive autoimmune skin care with aggressive anti-inflammatory treatments, careful wound care, and monitoring for secondary infections while addressing the underlying immune dysfunction.
Long-term Autoimmune Monitoring
Patients with lichen planus require ongoing assessment for associated autoimmune conditions, hepatitis C screening, and monitoring for potential malignant transformation, particularly in oral erosive disease.
Autoimmune Skin Care and Lifestyle Modifications
Comprehensive lichen planus management extends beyond medication to include specialized autoimmune skin care routines and lifestyle modifications that support immune system balance.
Gentle skin care practices, stress management techniques, and avoiding known triggers help minimize autoimmune flares. Patients learn appropriate oral hygiene for mucosal disease and protective measures to prevent trauma that may trigger new lesions.
Associated Autoimmune Conditions
Lichen planus patients show increased prevalence of other autoimmune conditions requiring comprehensive evaluation and coordinated care for optimal outcomes.
Studies demonstrate associations with autoimmune thyroid disease, hepatitis C infection, and various circulating autoantibodies. The chronic inflammatory nature of lichen planus may contribute to increased risk of cardiovascular disease and metabolic complications.
Treatment Response and Autoimmune Disease Monitoring
Successful lichen planus management requires ongoing monitoring of treatment response, side effects, and potential disease complications while maintaining optimal autoimmune system balance.
Regular follow-up appointments allow for treatment adjustments, assessment of new lesions, and monitoring for associated conditions. Many patients require long-term maintenance therapy to prevent disease recurrence and manage the chronic autoimmune nature of this condition.

Frequently Asked Questions About Lichen Planus
While lichen planus is a chronic autoimmune condition, it’s generally not life-threatening, though oral erosive forms require careful monitoring for potential malignant transformation.
No, lichen planus is not contagious as it represents an autoimmune process where the patient’s own immune system attacks healthy tissues.
Cutaneous lichen planus often resolves within 1-2 years, though recurrence is common, while oral forms tend to be more persistent and require long-term management.
Stress, certain medications, dental amalgam allergies, and hepatitis C infection can trigger or worsen lichen planus in susceptible individuals.
Treatment duration varies based on disease severity and response, with some patients requiring ongoing immunosuppressive therapy while others achieve remission with shorter courses.

Board-Certified Dermatologist Serving Cincinnati, Ohio
Dr. Kristine Zitelli is a board-certified dermatologist serving the Cincinnati area, known for her expertise in treating a wide range of skin conditions. She completed her medical degree at Wright State University and dermatology residency at the University of Cincinnati, with additional advanced training at the UCSF Psoriasis and Skin Treatment Center. Her clinical focus includes thorough skin examinations, psoriasis, eczema, complex medical dermatology, surgical dermatology and cosmetic treatments using the latest technologies.
Dr. Zitelli has been named a “Top Doctor” in Cincinnati every year since 2016 as well as Cincinnati’s Top Dermatologist in 2020. She remains dedicated to educating the community about skin health and sun safety. Combining academic excellence, clinical research, and a compassionate approach, Dr. Zitelli delivers personalized, evidence-based care to every patient.
Specialized Lichen Planus and Autoimmune Skin Care in Cincinnati
Don’t let this complex autoimmune condition control your quality of life. Dr. Zitelli’s comprehensive approach to lichen planus treatment combines advanced autoimmune therapies with personalized skin care strategies, helping patients in Cincinnati and Montgomery achieve optimal disease control and improved comfort. Schedule your specialized autoimmune skin care consultation today to begin your journey toward effective lichen planus management.