Squamous cell carcinoma (SCC) represents the second most common form of skin cancer. This cancer develops in the squamous cells of the skin’s outer layer and primarily results from cumulative ultraviolet radiation exposure, though it can also arise in areas with chronic wounds or more frequently in immunocompromised patients. While most SCCs have excellent cure rates when caught early, certain high-risk features can lead to local recurrence or metastasis if not properly treated.
Dr. Zitelli provides comprehensive squamous cell carcinoma management throughout Cincinnati, offering advanced surgical techniques including Mohs micrographic surgery, wide local excision, and specialized reconstructive procedures to achieve optimal cure rates while preserving function and cosmetic appearance for all SCC presentations.
Not only provides excellent care but truly cares.
Distinguishing SCC Types and High-Risk Features
Successful squamous cell carcinoma treatment requires accurate identification of tumor characteristics and risk factors that influence treatment selection and prognosis for optimal patient outcomes.
Well-Differentiated SCC Characteristics
Common form with good prognosis appearing as scaly, crusted bumps or non-healing sores on sun-exposed areas with low metastatic potential
Poorly Differentiated and Aggressive Variants
Higher-risk subtypes including infiltrative, desmoplastic, and adenosquamous forms requiring more aggressive surgical approaches and closer monitoring
High-Risk Location Considerations
SCCs on lips, ears, genitals, and areas of chronic scarring carrying increased recurrence and metastatic risks requiring specialized treatment protocols
Immunosuppression-Related SCCs
More aggressive tumors developing in organ transplant recipients or immunocompromised patients requiring intensive surveillance and treatment approaches
Advanced SCC Surgery and Mohs Excellence
Modern squamous cell carcinoma treatment employs multiple surgical approaches tailored to tumor risk factors, anatomical location, and patient characteristics for optimal cure rates.
Mohs Micrographic Surgery for High-Risk Cases
For higher risk SCC, Dr. Zitelli collaborates with leading Mohs surgeons in Cincinnati who utilize specialized microsurgical techniques to achieve precise tumor removal while preserving healthy tissue.
Wide Local Excision with Margin Assessment
Standard surgical approach for low-risk SCCs, involving complete tumor removal with appropriate safety margins and histopathologic confirmation
Sentinel Lymph Node Evaluation
Dr. Zitelli collaborates with top oncologic surgeons in Cincinnati, referring patients for advanced lymph node evaluation, guiding additional treatment decisions when indicated.
Risk Stratification and Treatment Planning
Comprehensive SCC care requires thorough evaluation of tumor and patient factors to stratify risk levels and select the most appropriate treatment approach for each individual case.
Dr. Zitelli’s systematic approach includes assessment of tumor size, depth, differentiation grade, anatomical location, and patient immune status. This detailed evaluation guides treatment selection between standard excision and Mohs surgery while determining need for additional staging or adjuvant therapies.
Post-Treatment Surveillance and SCC Prevention
Effective long-term management of squamous cell carcinoma extends beyond initial treatment, encompassing structured follow-up and proactive prevention strategies, especially critical for high-risk patients with an elevated likelihood of developing subsequent skin cancers.
Understanding that SCC patients face increased risks for developing new skin cancers guides our surveillance approach. Regular skin examinations, sun protection education, and early detection training help identify concerning changes when they remain small and easily treatable.
Frequently Asked Questions About Squamous Cell Carcinoma
While most SCCs are highly curable with proper treatment, they have higher metastatic potential than basal cell carcinomas, particularly in high-risk locations or immunocompromised patients.
High-risk features include large size, poor differentiation, location on lips or ears, depth of invasion, and occurrence in immunosuppressed patients, all of which increase recurrence and metastatic risks.
Mohs surgery is often recommended for high-risk SCCs, recurrent tumors, and those in cosmetically sensitive areas.
With appropriate surgical treatment, recurrence rates are typically less than 5% for standard excision and even lower with Mohs surgery, though high-risk features can increase these rates.
Most SCCs require only surgical removal, but high-risk cases may benefit from radiation therapy or systemic treatments, particularly if lymph node involvement is detected.
Board-Certified Dermatologist Serving Cincinnati, Ohio
Dr. Kristine Zitelli is a board-certified dermatologist serving the Cincinnati area, known for her expertise in treating a wide range of skin conditions. She completed her medical degree at Wright State University and dermatology residency at the University of Cincinnati, with additional advanced training at the UCSF Psoriasis and Skin Treatment Center. Her clinical focus includes thorough skin examinations, psoriasis, eczema, complex medical dermatology, surgical dermatology and cosmetic treatments using the latest technologies.
Dr. Zitelli has been named a “Top Doctor” in Cincinnati every year since 2016 as well as Cincinnati’s Top Dermatologist in 2020. She remains dedicated to educating the community about skin health and sun safety. Combining academic excellence, clinical research, and a compassionate approach, Dr. Zitelli delivers personalized, evidence-based care to every patient.
Trusted Squamous Cell Carcinoma Treatment in Cincinnati
Achieve optimal outcomes for your squamous cell carcinoma with proven surgical expertise and individualized care. Dr. Zitelli’s comprehensive approach to SCC treatment provides Cincinnati patients with advanced surgical techniques, thorough risk assessment, and ongoing surveillance for the highest cure rates and best functional outcomes.
Schedule your SCC consultation today to receive specialized care that combines cutting-edge treatment with personalized attention to your unique needs and concerns.
